Mass Effect 2
Two years after Commander Shepard repelled invading Reapers bent on the destruction of all organic life, a mysterious new enemy has emerged. On the fringes of known space, entire human colonies are vanishing. As Commander Shepard, you must assemble the galaxy's deadliest team and stop the most terrifying threat humanity has ever faced.
Even then, they call it a suicide mission. Prove them wrong and save mankind.