• Unique Interactive Experience -- All aspects of the game will be controlled on the Nintendo DS touch screen, including batting, pitching, fielding and baserunning.
• Exciting Gameplay Modes -- Exhibition mode will allow players to quickly choose their favorite teams so they can immediately jump into the intense baseball action, while Fantasy Pennant mode will offer various tournaments to compete in. All-Star Training will assist players in learning the fundamental DS control functions wrapped up in a variety of fun and challenging mini-games.
• All-Star Lineups -- Players can create their own unique baseball teams by choosing from the different starting lineups and putting together their favorite All-Stars.
• Uniquely Themed Stadiums -- Set in extreme environments that portray the diverse North American environment, uniquely themed stadiums are in locations ranging from the Everglades in Florida to the Frozen North, locations that can only be mastered by the best.
• Multi-player -- Supports two-player DS Wireless and Nintendo Wi-Fi Connection. For added competitiveness, Major League Baseball 2K8 Fantasy All-Stars will utilize DS Wireless and Nintendo Wi-Fi Connections so players can go head-to-head in intense worldwide multi-player gaming.

Adding to the addictive gameplay experience, players will also have the ability to obtain special power ups to complete incredible batting, pitching, and fielding performances. Players can force their opponents to chase after the chicken ball that runs away from fielders once it's on the ground, or confuse them with a crazy ball that takes an unpredictable flight path. Pitchers can throw amazing new pitches such as a super splitter that splits the ball into two pieces to confuse the batter or a fireball that screams over the plate at rocket speeds while engulfed in flames. Fielders can join in the power up fun with the brick wall that causes a wall to instantly rise out of the ground to stop the ball in its tracks or the super jump that allows them to jump incredibly high toward the ball in flight.