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Sebastian Caine heads a top-secret research project to unlock the secret of invisibility. When the formula works successfully on animals, an ecstatic Caine recklessly disobeys orders and experiments on himself. Unfortunately, the dangerous gamble goes terribly wrong when the procedure cannot be reversed. Caine and his chief lieutenants Linda McKay and Matt Kensington, frantically attempt to counteract the effect. But the invisible Caine, fueled by latent megalomaniac tendencies, quickly becomes intoxicated with his newfound power. The laboratory becomes a house divided as the scientists realize their suddenly omnipotent leader perceives them as a threat to his very existence.